In view of the recent demonstration that antibodies that are protective agains Plasmodium falciparum malaria may act in collaboration with blood monocytes, we have investigated the isotype content of sera from individuals with defined clinical states of resistance or susceptibility to malaria.Profound differences in the distribution of each Ig subc
Long COVID in patients with rheumatologic disease: A single center observational study
Background: Special attention has been paid to shave cream the sequelae caused by SARS-CoV 2 infection (Long-COVID), the prevalence of these sequelae in patients with rheumatological diseases has not been studied in detail.As these patients have immunosuppressive therapy and this syndrome has inflammatory characteristics, we postulate that these pa
COVID-19 strategy in organizing and planning orthopedic surgery in a major orthopedic referral center in an area of Italy severely affected by the pandemic: experience of the Department of Orthopedics, University of Padova
Abstract Background According to the required reorganization of all hospital activities, the recent COVID-19 pandemic Table Runner had dramatic consequences on the orthopedic world.We think that informing the orthopedic community about the strategy that we adopted both in our hospital and in our Department of Orthopedics could be useful, particular
New biomarkers of bone remodelling regulation in patients with acromegaly and endogenous hypercortisolism
Background: Bone tissue is a non-classical endocrine organ, which produces at least two hormones: fibroblast growth factor 23 (FGF-23) and decarboxylated osteocalcin (OC).In addition to this, recent studies demonstrate that specific proteins involved in the paracrine regulation of bone remodelling can be measured in peripheral serum samples and may
How do eubacterial organisms manage aggregation-prone proteome? [v1; ref status: indexed, http://f1000r.es/3k3]
Eubacterial genomes vary considerably in their nucleotide composition.The percentage of genetic material constituted by guanosine and cytosine (GC) nucleotides ranges from 20% to 70%.It has been posited that GC-poor organisms are more dependent on protein folding machinery.Previous studies have ascribed this to the accumulation of mildly deleteriou